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You are very lucky that you found a Chiropractor that is that knowledgeable. I came across this blog the other day. Very informative. I had been using MethylFolate the wrong way. This doctor's blog says to take it on an empty stomach. It does seems to makes a difference. I wish I had known sooner.

@DW2945 - Conventional Medical doctors are uninterested because they don't get paid to help you get well. They get paid to keep you coming back, they get paid for prescribing medication and procedures. You need to find a non-conventional doctor, and not necessarily a Naturopath, as they can be just as bad as conventional Drs. I had a Naturopath who wanted to keep prescribing me thyroid meds when it was obvious they were not helping. Only when I went to a Chiropractor who specializes in Autoimmune conditions did I finally find someone who actually helped me! He is able to read these reports and knows what we need.

I have Hashi's and homozygous for for C677T. Poor conversion of t4 to t3 as well. After Cytomel and Naturethroid, antibodies went from 157 to 17. Supplement with Milk Thistle for liver to convert t4 to t3. I am homozygous for 10 other MTHFR and MTHF.

I have the MTHFR C677T, with a +/-.which my doctor says has to do with B vitamins, Liver function and methylation.

I have been off ALL prescription Thyroid meds since March 15, 2011 - over 6 years. One month after being off the meds, I really felt the difference. No more anxiety, less stress, my eczema was GONE! Of course, I made a LOT of changes in my diet and supplement regimen. No gluten, dairy, soy, corn, peanuts products, pork, shellfish, mollusks. Trying to eliminate sugar because I feel so much better without sugar. I do take natural, whole food supplements. Probably spend as much per month on supplements as I would have spent on prescriptions and OTC meds, as insurance only covers so much. I sleep better, I lose the belly, aches and pains are almost non-existent, inflammation is gone. As of now, I am on NO prescription or over the counter medications. I hardly ever have headaches, and I know when I do get a headache, it is likely I just need to drink some water or go outside to clear the toxins and breathe non-chemical laden air (fragrances, cleaning products, carpeting).

Hashimoto's can be managed without prescriptions ... More

I have the MTHFR C677T, with a +/-.which my doctor says has to do with B vitamins, Liver function and methylation.

I have been off ALL prescription Thyroid meds since March 15, 2011 - over 6 years. One month after being off the meds, I really felt the difference. No more anxiety, less stress, my eczema was GONE! Of course, I made a LOT of changes in my diet and supplement regimen. No gluten, dairy, soy, corn, peanuts products, pork, shellfish, mollusks. Trying to eliminate sugar because I feel so much better without sugar. I do take natural, whole food supplements. Probably spend as much per month on supplements as I would have spent on prescriptions and OTC meds, as insurance only covers so much. I sleep better, I lose the belly, aches and pains are almost non-existent, inflammation is gone. As of now, I am on NO prescription or over the counter medications. I hardly ever have headaches, and I know when I do get a headache, it is likely I just need to drink some water or go outside to clear the toxins and breathe non-chemical laden air (fragrances, cleaning products, carpeting).

Hashimoto's can be managed without prescriptions. In fact, I'm convinced, and am testimony to the fact that the prescription Thyroid meds actually made my health worse.  Less

Yes, homo for c677t.

Yes, me as well. Hashimoto's onset in the first trimester of my second pregnancy. Subclinical hypothyroid in my first pregnancy.

Have any of you looked at your result for FOXE gene? That's a gene that when mutated is predisposition to thyroid issues

Yes,

About 40% of people with Hashimoto's will be heterozygous and about 9% will be homozygous.

About 40% of people with ingrowing toenails will be heterozygous and about 9% will be homozygous.

Of course, about 40% of people without Hashimoto's will be heterozygous and 9% homozygous.

That's why you can't rely on anecdotal reporting (like in this thread) and why you need to look at proper, large-scale, peer-reviewed scientific studies.

Using anecdotes to propose a link between the C677>T mutation and Hashimoto's is as pointless as using it to propose a link with MTHFR and ingrowing toenails.

@WX3709, if you had trouble with NDT, please check this out:
https://stopthethyroidmadness.com/ndt-doesnt-work-for-me/

I have the CTLA4 gene and also cannot convert thyroid meds. I'm on a last ditch hope with T3 only meds after massively failing with Levo and NDT.

Thanks, @@VA6919 and @BE6334! Great ideas I will pursue!

@RP4772 after following STTM I now take NDT with T3. Still a way to go yet but better than I was.
B12 to sort next.
Thanks for the heads up on the CTLA4 gene - I'll look into it.

i would also check the CTLA4 gene - I have hashi and MTHFR hetero mutations - but the CTLA4 gene is where I have the homozygous mutation... I am on NDT after my body couldn't convert the levothyroxin properly. best thing in the world. stopthethyroidmadness.com is fantastic.

I have hashis and homo c677t

If you've done the 23andme and have uploaded it to Livewello... Dr Kendall Stewart is an ANAZING neurosurgeon I. Austin Texas that has seen 13 people in my family and relatives. He has people come from all over the US to see him and he will sit down and tell you every single genetic mutation and their cause and then he puts you on a path to wellness without big pharma ! Watch him on YouTube . He is an unbelievably intelligent man!

I have Hashi's and am heterozygous MTHFR C677T. I take a natural WP for the hashi's, and have watched Dr. Izabella Wentz's videos and articles. I found out years ago that I have both of these, and within the last several months have started to watch, even more so, what I eat. She put hers into remission, I'm hoping to maybe do the same thing. I've cut out added sugar, gluten-free, tomatoes when possible. Nightshades including potatoes, and Chocolate. I've added more fish to my diet. I've also started taking Betaine HCL to help process protein, for me mainly meats. My blood gets checked at least twice per year. I am also taking a natural form of progesterone and estrogen. My Naturopath recommended taking MethylFolate. All of my supplements are without Folic Acid. Most people would be appalled at seeing my cache of supplements, Methylcobalamin B-12, Zinc, recently added Selenium, B-Complex w/o Folic Acid, Quercetin Bromelain, Magnesium Citrate, Vitamin C, NAC, MAX-Q10, Astaxanthin, 5,000 Vitamin D3 (I don't uptake it well), Pure Osteo Vegan for Calcium/K2/D3 and a myriad of vitamins and minerals, Astragalus (great immune support) also ... More

I have Hashi's and am heterozygous MTHFR C677T. I take a natural WP for the hashi's, and have watched Dr. Izabella Wentz's videos and articles. I found out years ago that I have both of these, and within the last several months have started to watch, even more so, what I eat. She put hers into remission, I'm hoping to maybe do the same thing. I've cut out added sugar, gluten-free, tomatoes when possible. Nightshades including potatoes, and Chocolate. I've added more fish to my diet. I've also started taking Betaine HCL to help process protein, for me mainly meats. My blood gets checked at least twice per year. I am also taking a natural form of progesterone and estrogen. My Naturopath recommended taking MethylFolate. All of my supplements are without Folic Acid. Most people would be appalled at seeing my cache of supplements, Methylcobalamin B-12, Zinc, recently added Selenium, B-Complex w/o Folic Acid, Quercetin Bromelain, Magnesium Citrate, Vitamin C, NAC, MAX-Q10, Astaxanthin, 5,000 Vitamin D3 (I don't uptake it well), Pure Osteo Vegan for Calcium/K2/D3 and a myriad of vitamins and minerals, Astragalus (great immune support) also it is adaptogenic. Another adaptogenic herb I take is Ashwagandha. I take a Complete Probiotics, and Chlorella for heavy metals detox. Recently have added Calcium D-Glucarate to help with detox, and Berberine for Glucose Metabolism...and lastly I take MSM which has really helped my hair from falling out and has strengthened it.. Oh, and trying to heal my gut as apparently if you have Hashi's, you do have leaky gut, I have been using Bone Broth and Collagen. I've lost at least 10 pounds, but have stagnated as not exercising as much as I should be. Hope this helps someone. Less

Yes, me. Am heterozygous for all eight MTHFR genes do have Hashimoto's.
I'm just two months into four months without B12 supplements to see if that is affected too.

Yes, me. Am heterozygous for all eight MTHFR genes do have Hashimoto's.
I'm just two months into four months without B12 supplements to see if that is affected too.

my sister is homozygous for c677T and has hashimotos.

@dw2945
I used https://knowyourgenetics.com/ and input my raw data. Have you looked at b12 deficiency? I recently learned I have another mutation called tcn1 & tcn2 (there's also gif) where ingested b12 is not fully protected from stomach acid (intrinsic factor, or IF) and then doesn't make it to the gut to be absorbed, leading to deficiency. I fixed everything and STILL had fatigue. Methyl B12 injections have changed my life!!!
I also have a FB group I started with another gal to discuss connections between MTHFR and lots of other things - autoimmune, leaky gut, vaccine injuries (since MTHFR kids have a hard time detoxing the ingredients), autism, lip & tongue ties, etc. https://www.facebook.com/groups/MTHFRconnections/