Warfarin and CYP2C9 drugs

Warfarin is used to prevent blood clots from forming or growing larger in your blood and blood vessels. It is prescribed for people with certain types of irregular heartbeat, people with prosthetic (replacement or mechanical) heart valves, and people who have suffered a heart attack. Warfarin is also used to treat or prevent venous thrombosis (swelling and blood clot in a vein) and pulmonary embolism (a blood clot in the lung). Warfarin is in a class of medications called anticoagulants ('blood thinners'). It works by decreasing the clotting ability of the blood.

Variations of the CYP2C9 and VKORC1 genes can decrease a persons ability to break down warfarin, which causes the drug's effect to last longer, resulting in the need for lower doses.

Related to:
Coumadin, Jantoven